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Hair Cloning
The thought of being able to culture hair follicles
and have an unlimited donor supply has been a
long-time dream of patients with hair loss and hair
restoration surgeons alike. The obstacles, however,
have seemed enormous since the hair follicle is a
very complex structure of skin cells, blood vessels,
nerves, muscles, and glands. (As an analogy,
culturing a hair follicle would be more like
culturing an entire eyeball rather than just the
cells of the cornea.) Now there is hope that not
only is cloning possible, but that this hair may not
even need to be your own.
Dr. Colin Jahoda, a British scientist recently
reported that he took dermal sheath cells (cells
from the lowest part of the hair follicle) from his
own scalp and transplanted them into his wife's
forearm. These implanted cells then stimulated his
wife's skin to grow new hair. The hair was analyzed
by Dr. Angela Christiano at Columbia University in
New York and was show to be composed of cells with
Dr. Jahoda's XY chromosomes at the bottom and his
wife's XX chromosomes at the top.
This clever experiment shows that the hair
follicle's dermal sheaths cells are one of the
bodies "immune privileged" organs, enabling them to
be transplanted from one person to another without
rejection. More importantly, this study suggests
that all one might need to do is to transplant these
"inducer" cells to stimulate new hair growth, rather
than having to transplant the entire follicle
itself. The great significance, for those that are
balding, is that these cells may some day be
cultured in the lab, to produce a potentially
unlimited supply of hair.
Although, this was just one preliminary study, the
work provides a clear direction for further cloning
research and gives considerable hope that the
technology may be available in the not too distant
future. Stay tuned!
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