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Posts Tagged ‘Hair Loss’

Breakthrough in Prostaglandin Leads to Answers for Hair Loss in Men and Women

April 4th, 2012

Recent break­through by the Perel­man School of Med­i­cine at the Uni­ver­sity of Penn­syl­va­nia have found that an abnor­mal amount of a lipid pro­tein called Prostaglandin D2 in men with andro­ge­netic alope­cia may be the cause for hair loss in men and women. The deriv­a­tive of prostaglandin in a cer­tain recep­tor is inhibit­ing hair growth in both human as well as ani­mal sub­jects. Strik­ing 8 out of 10 men under 70 male pat­tern bald­ness causes hair fol­li­cles to shrink and grow micro­scopic hair for a shorter time lapse than nor­mal.




Ear­lier research last year found that hair from bald scalp as well as from non-bald scalp con­tained the same amount of stem cells as well as find­ing the deple­tion of a prog­en­i­tor cell. Tak­ing an unbi­ased look when search­ing for poten­tial organic causes for bald­ness, look­ing at scalp tis­sue for bald and non-bald hair fol­li­cles, they found that in human as well as in ani­mal sub­ject the pres­ence of the deriv­a­tive pro­tein was 3 times higher than found in sim­i­lar haired scalp with men with male pat­tern bald­ness. Although no clin­i­cal tri­als are under­way at this time this dis­cov­ery raises expec­ta­tion to bring about new hair loss treat­ments in men and women.


 

Female Pattern Baldness Treatments

February 21st, 2012

Clin­i­cal fea­tures of pat­tern bald­ness in women usu­ally occur dur­ing early teens and late mid­dle age. This is shown by the grad­ual thin­ning of hair over the frontal area. Usu­ally, pat­tern bald­ness in women is not accom­pa­nied by increased shed­ding of hair, but unlike tel­o­gen efflu­vium, hair loss may be seen from the start. The scalp becomes more and more vis­i­ble as the dis­ease progresses.

 
Most of the time, the cen­tral part of the head widens due to dif­fused reduc­tion of the hair’s den­sity, which involves the frontal scalp and crown. Some women may expe­ri­ence hair loss on some small areas of the frontal scalp while oth­ers may expe­ri­ence the effect on the entire scalp includ­ing the areas of pari­etal and occip­i­tal. Dur­ing hair loss, women usu­ally retain a rim of hair along the frontal hairline.
 
Lab­o­ra­tory Evaluation
Most women with pat­tern bald­ness have nor­mal men­stru­a­tion, nor­mal fer­til­ity, and nor­mal endocrine func­tion, includ­ing cor­rect lev­els of cir­cu­lat­ing andro­gens. There­fore, they would only need exten­sive hor­monal test­ing when symp­toms and signs of andro­gen excess become really vis­i­ble. Lab­o­ra­tory mea­sure­ment of serum total or free testos­terone, dehy­droepiandros­terone sul­fate and pro­lactin are appro­pri­ate when hir­sutism, severe unre­spon­sive cys­tic acne, vir­il­iza­tion, or galac­t­or­rhoea are present. Mea­sure­ment of serum thy­rotropin, serum iron and fer­ritin, and com­plete blood count may elim­i­nate com­mon causes of hair loss.
 
Dif­fer­en­tial Diag­no­sis of Andro­ge­netic Alopecia
Andro­ge­netic alope­cia in women (exter­nal link) can be con­fused with the for­mer con­di­tion. This is in spite of the fact that fea­tures of chronic tel­o­gen efflu­vium are dis­tinct. Any­way, hor­i­zon­tal sec­tions of a scalp biopsy help to dis­tin­guish the two con­di­tions once the ratio of ter­mi­nal hairs shrinks.
 
Mor­phol­ogy
As time goes by, the hairs in pat­tern bald­ness become pro­gres­sively minia­tur­ized. These hairs include the papil­lae and matri­ces, as well as the hair shafts. How­ever, the degree of hair loss in women is not as extreme as it is with some men. Women with pat­tern hair loss have a mosaic of variable-diameter hairs in the affected region of the top of the scalp. Increased spac­ing between hairs makes the cen­tral part appear wider over the frontal scalp com­pared to the occip­i­tal scalp.
 
In some cases, hair vol­ume may still appear nor­mal but the hair would stop grow­ing to its pre­vi­ous length and nor­mally results to thin dis­tal ends. Female pat­tern hair loss is seen on women by visual decrease in hair den­sity while in men, it is by bald­ness on the affected areas.
 
Treat­ment of Andro­ge­netic Alopecia
Hair loss is a result of abnor­mal hair cycle. Because of this, it is the­o­ret­i­cally reversible. How­ever, the cur­rent treat­ment options have lim­its in their per­for­mance and in some cases, only small improve­ments in hair den­sity can be seen. Advanced pat­tern bald­ness may already be dif­fi­cult to treat because irrepara­ble dam­ages may have already taken place on the fol­lic­u­lar stem cell when inflam­ma­tion sur­rounded the bulge area of the fol­li­cle. Some sys­tem­atic treat­ment plans for this case include:
 
 
The cur­rent treat­ment for pat­tern bald­ness is Minox­i­dil. The exact mech­a­nism by which Minox­i­dil works is not known but the treat­ment appears to affect the hair fol­li­cle in three ways: it increases the span of time fol­li­cles spend in ana­gen, it rouses fol­li­cles that are in cata­gen and it enlarges the actual follicles.
 
Hair Loss In Women
 
 
In effect, vel­lus hairs enlarge and are con­verted to ter­mi­nal hairs, and shed­ding is reduced.Exoge­nous estro­gen can be used to treat pat­tern bald­ness, but this reg­i­men is no longer much in use because of Minoxidil’s efficacy.

Finas­teride has been effec­tive on men with pat­tern bald­ness but def­i­nitely it was risky on women. This reg­i­men is not advis­able for women who are still in their child­bear­ing age because of the pres­ence of 5a-reductase inhibitors that may cause exter­nal gen­i­talia abnor­mal­i­ties in male fetuses.

Hair­styling, teas­ing, col­or­ing, per­ma­nents, and the use of hair spray are means of cop­ing with the cos­metic effects of pat­tern bald­ness. How­ever, when the hair loss is grave, the affected per­son may opt to use wigs.

Hair trans­plan­ta­tion is another option since it has already been accepted in treat­ing pat­tern bald­ness on men. Now, it is also being used to treat female hair loss although only a very few women go for this type of treat­ment because of the cost and the pos­si­ble trauma that may go with it.

For those women who have encoun­tered inef­fec­tive and unsuc­cess­ful treat­ments for hair loss, surgery may be another option and thus, the most suited method for them.

Hair Loss | DHT The Hair Killer

February 13th, 2012

Did you know that 95% of pat­tern bald­ness for both men and women is caused by hor­mone known as dihy­drotestos­terone? This nasty hor­mone sneaks up on your hair fol­li­cles and silently kills them, and the end result is make and female pat­tern baldness. 

Dihy­drotestos­terone is male hor­mones com­bi­na­tion com­monly found in both men and women of all ages. When an excess of this hor­mone is pro­duced, it can lead directly to the loss of your hair, com­monly known as genetic hair loss or male and female pat­tern baldness. 

This DHT hor­mone sur­round your hair fol­li­cles with ha wax like sub­stance; this will basi­cally starve the fol­li­cles of much needed vit­a­mins and nutri­ents that help them to grow healthy and strong hair. The DHT, causes your hair fol­li­cles to pro­duced thin­ner and thin­ner and more brit­tle hairs until the sim­ply fall out, and new hair are unable to replace them due to dam­ages DHT has done to the fol­li­cle. Leav­ing you with those tell tale unsightly bald patches or more com­mon in women thin­ning across your scalp.

But there is help in the best hair loss solu­tion, these clin­i­cally proven for­mu­la­tions can and do work to stop the loss of your hair and help-grow your own nat­ural and sexy healthy hair. These hair loss reme­dies use the only FDA approved ingre­di­ent on the mar­ket that can be used by both men and women and has been proven to help stop fur­ther hair loss and re-grow hair.

The top­i­cal hair loss solu­tion goes to work ensur­ing your fol­li­cles receive a rich sup­ply of hair friendly clods filled with the vit­a­mins and nutri­ents needed to help those hairs grow to be strong healthy and shiny.

Com­bine this with the oral min­eral and vit­a­min sup­ple­ments,. and you have a win­ning com­bi­na­tion for hair loss re-growth.

The vit­a­min and min­eral sup­ple­ments con­tain all nat­ural ingre­di­ents and herbs with pow­er­ful DHT block­ing abil­i­ties, thus ensur­ing your hair has the very vest chances to defeat the silent killer dihy­drotestos­terone.

Hair loss due to DHT

 

 

 

 

 

Hair Loss Dyeing and Bleaching

August 10th, 2011
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Self-esteem and sex appeal are so closely link that a recent sur­vey has revealed that over %24 of women have thin­ning hair or are expe­ri­enc­ing hair loss com­pletely.  One of hair’s pri­mary func­tions as a sec­ondary sex­ual char­ac­ter­is­tic is to keep us attrac­tive.  We live in a cul­ture of full, sexy hair being the def­i­n­i­tion of fem­i­nin­ity and attrac­tion.  Approx­i­mately 30 mil­lion women in the US, one in four, have to deal with the emo­tional cri­sis of hav­ing thin­ning hair with a daily reprieve con­tin­gent on the full­ness of their hair.

There are many rea­sons for non-genetic hair thin­ning or female hair loss.  Hair dye and bleach is the cause for many hair loss con­di­tions within the female pop­u­la­tions.  Music mega artist Lady Gaga for exam­ple has recently exposed the fact that she is using Rogaine for hair loss prob­lem due to con­stant dye­ing and bleach­ing of her hair.  Lady Gaga, 24 year old mega pop star openly admits to have been dying her hair from a nat­ural brunette to a plat­inum blond since launch­ing her career leav­ing her once full head of hair thin and unhealthy.

Dif­fer­ent treat­ments are rec­om­mended for hair loss; hair trans­plant surgery being one of them how­ever due to over dye­ing and bleach­ing lesser treat­ments might be effec­tive such as com­bin­ing Rogaine treat­ments with a solid reg­i­men of low level laser ther­apy, like only FDA approved laser ther­apy is Lex­ing­ton Hair­max laser comb, which is known to stim­u­late growth and grow thicker, fuller and over­all health­ier hair.

Beverly Hills Hair Restoration: Committed to Confidentiality

August 8th, 2011
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When com­mit­ting to being in the pub­lic eye, are you com­pro­mis­ing your right to hav­ing med­ical con­fi­den­tial­ity  Not nece­sarely.   Bev­erly Hills Hair Restora­tion has clien­tele in and out of the pub­lic eye; peo­ple come form all over the world to see Dr. Kahen for his expe­ri­ence as well as his integrity in being able to main­tain the out­most con­fi­den­tial­ity regard­ing who his patients are.

As a world known Bev­erly Hills Hair Trans­plant Sur­geon, Dr. John Kahen has been numer­ously asked about his celebrity clien­tele by many. Recently Dr. Kahen got a phone call from celebrity gos­sip and enter­tain­ment news media leader, TMZ.  Due to the nature of the phone call and his com­mit­ment to the integrity of his prac­tice, Dr. Kahen was unable to dis­close to any­one includ­ing TMZ any infor­ma­tion regard­ing whom he has treated for hair loss or per­formed hair trans­plant surgery on.

Bev­erly Hills Hair Restora­tion Clinic is con­ve­niently located in the heart of Bev­erly Hills, Cal­i­for­nia.  We offer secured under­ground park­ing that is eas­ily acces­si­ble to the ele­va­tor, which will take you straight to the safety of Dr. Kahen’s office with­out hav­ing to com­pro­mise your secu­rity, con­fi­den­tial­ity and com­fort before and after your surgery.

Hair Transplant: Getting to the Root

July 29th, 2011
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It seems like not even a month goes by with­out hav­ing another male celebrity share their expe­ri­ence with hair trans­plant surgery.Hair trans­plant clin­ics that are part­ner­ing up with celebri­ties for endorse­ment part­ner­ships are a grow­ing trend nowa­days.  It’s esti­mated that annu­ally 10,000 men are resort­ing to sur­gi­cal help to aid them with their hair loss and hair thin­ning issues.  Hair-loss clin­ics are sprout­ing all over town at avery alarm­ing rate.  Pro­fes­sion­als such as den­tists are get­ting involved in hair replace­mentprac­tices to help restore fol­lic­u­lar fortunes.

So, how can poten­tial patients know if they qual­ify for fol­lic­u­lar hair trans­plant  If so, how to qual­ify a doctor

The qual­i­fy­ing fac­tors for being a can­di­date for hair trans­plant surgery are basi­cally two;  fol­lic­u­lar hair trans­plant it involves trans­plant­ing hair form areas of rel­a­tive excess such as the back of the head or in some cases the sides to the top of the head.  The other deter­min­ing fac­tor is being at the lower end of the scale that way you will have ample sup­ply for the demand.  Not all male hair loss meets this criterion.

Male pat­tern hair loss if mea­sured in seven stages called the Nor­wood scale, after Dr. O’Tra Nor­wood, the Amer­i­can der­ma­tol­o­gist who explained in the 1970’s.  Men at the lower end of the scale do very well with hair trans­plant pro­ce­dures, while men on the higher end — the demand may out strip the supply.

It’s imper­a­tive to think about the future when con­sid­er­ing hair replace­ment surgery due to the fact that male pat­ter bald­ness is pro­gres­sive.  A skill­ful doc­tor will let you know when is cool to oper­ate and when it’s not.

A sin­gle hair trans­plant oper­a­tion requires any­where between 4,000 — 5,000 grafts of hair fol­li­cles.  The donor hair is removed from the back of the head by a lin­ear hor­i­zon­tal inci­sion then the expe­ri­enced sur­gi­cal team care­fully dis­sects each fol­lic­u­lar unit that will the be gen­tly placed in the tiny inci­sions cre­ated to be placed one by one.

This process can take hours, that is why this surgery has to be done by a qual­i­fied sur­geon that has the level of expe­ri­ence to do this well, the hair trans­plant costs asso­ci­ated with these types of pro­ce­dures have been seen as high as $60,000.

Stop Living With Hair Loss

July 28th, 2011
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Thanks to hair trans­plant surgery, you don’t have to live with hair loss for the rest of your life. This arti­cle looks at four impor­tant tips that can help you get great suc­cess with the procedure.

Tip #1: Do your research, to get the right sur­geon. Hair replace­ment surgery can give you very suc­cess­ful results. Many peo­ple now have full as well as nat­ural look­ing hair after just one sur­gi­cal session.

Tip #2: Read about the patients’ expe­ri­ence. With the awe­some power of the Inter­net, there are lots of dis­cus­sion groups and forums out there where you can find real-life peo­ple that have had suc­cess­ful trans­plant done. Talk to them and learn, first-hand, what they went through, their suc­cesses or fail­ures and where to find the best sur­geons. You can even view real-life before and after pho­tos to help you decide.

Tip #3: Take the time to thor­oughly research and pick a sur­geon with an out­stand­ing rep­u­ta­tion. While there are many sur­geons, not all of them have the expe­ri­ence and skills nec­es­sary to pro­vide you with the results you wish to achieve. A doc­tor can have 20 years of expe­ri­ence but very lit­tle expe­ri­ence in new meth­ods. Expe­ri­ence the doc­tors who prac­tice new meth­ods are the sur­geons who pro­vided supe­rior and nat­ural result.
Tip #4: Con­tact exist­ing patients and get your ques­tions answered by some­one who went through the process. In doing so, you’ll obtain first-hand knowl­edge of how your expe­ri­ence will be with the sur­geon you’re elect­ing to per­form hair restora­tion. Go through the exist­ing patients to select the best sur­geon. Patients can be relied on the most hon­est and infor­ma­tive rec­om­men­da­tions, insur­ing you chose to the best hair trans­plant sur­geon, based on skill and most impor­tantly the results.
As sim­ple as the above tips are they can really help you get great suc­cess with hair trans­plant surgery

Genetic Testing: HairDX

July 26th, 2011
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HairDX is a genetic test that will aid the doc­tor in deter­min­ing your hair loss pat­tern before it occurs aid­ing in deter­min­ing what is the best course to fol­low in the treat­ment that will have the high­est like­li­hood of suc­cess in hair loss pre­ven­tion.

The X and Y-chromosomes deter­mine your gen­der, while andro­gens are the hor­mones that deter­mine sec­ondary sex char­ac­ter­is­tics, which help dis­tin­guish the appear­ance of men from women.  By per­form­ing this test and see­ing the pat­tern in your fam­ily his­tory as well as in your geneal­ogy the doc­tor will be able to pre­dict your pre­dis­po­si­tion for hair loss or hair thin­ning.  In most cases by the time hair loss or thin­ning starts to get notice­able as much as 50% of the hair loss could have already occurred.

Is there a way to pre­dict hair loss or thin­ning before this takes place  Absolutely!  HairDX will pre­dict hair loss before vis­i­ble signs start to make them­selves vis­i­ble, edu­cated deci­sions can then be made to pre­serve the exist­ing hair, tak­ing in con­sid­er­a­tion that FDA approved treat­ments are best at pre­serv­ing exist­ing hair rather that re-growing of new hair.

For female hair loss, HairDX genetic test­ing will deter­mine the CAG repeat score for women to deter­mine the like­li­hood of female pat­ter bald­ness, a lower CAG score (Lud­wig grade II or III hair loss) means a higher risk for sig­nif­i­cant hair loss while a higher score meant the oppo­site.  Research has show that only 2.3% of women with a CAG test score bel­low 15 didn’t develop female pat­tern hair loss.  Stud­ies have also showed that 50% of women over the age 60 will expe­ri­ence some form of female pat­tern bald­ness.

Just like any other type of med­ical con­di­tion, for males as well as females, early detec­tion will most def­i­nitely give you a plethora of choices when it comes to hav­ing full and healthy hair.

The HairDX Genetic Test for Andro­ge­netic Alope­cia (AGA), the most com­mon form of hair loss in men and women is avail­able with Dr. John Kahen at Bev­erly Hills Hair Restora­tion.  If you would like to learn more about the HairDX Genetic Test and receive a com­pli­men­tary con­sul­ta­tion click here!

Can your Shampoo be causing unnecessary hair loss?

July 7th, 2011
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Most sham­poos cause hair loss, SLS (Sodium Lau­ryl Sul­fate) is a key com­po­nent in 95% of sham­poos that has been sin­gled out as the cul­prit.  Is your sham­poo such a bad boy  It doesn’t have to be, SLS is a potent de-greaser, leav­ing your hair clean by bind­ing the grease and dirt together leav­ing it bouncy and clean.

The prob­lem starts after you rinse your hair due to the residue SLS leaves by set­ting up camp in as well as on our scalp.  Stud­ies show that as part of the nor­mal hair cycle the aver­age per­son sheds about 100 hairs a day; leav­ing the hair fol­li­cle exposed to an SLS irri­ta­tion caus­ing the pos­si­ble death of that fol­li­cle and not allow­ing for regen­er­a­tion caus­ing hair loss.   SLS free sham­poos AKA SLES free sham­poos or sul­fate free sham­poos are one of the hottest and trendi­est prod­ucts to hit the health-conscious beauty mar­ket­place pre­vent­ing hair loss. The inex­pen­sive and pow­er­ful sur­fac­tants in SLS make this agent a cost effec­tive choice for sham­poos (as well as house hold deter­gents), espe­cially the inex­pen­sive ones.  Sul­fate free sham­poos are unfor­tu­nately dif­fi­cult to find and are often on the expen­sive side due to the higher qual­ity ingre­di­ents they require.

In addi­tion sul­fate free sham­poos may leave your hair feel­ing “dif­fer­ent” than tra­di­tional sham­poos because of the alter­na­tive sur­fac­tants usu­ally found in plant extracts.  Switch­ing to a sul­fate free sham­poo might be more expen­sive, how­ever it’s money well spent when you con­sider the health ram­i­fi­ca­tions and to stop hair loss.

Can Stem Cell Cloning Really Cure Hair Loss?

June 14th, 2011
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Stem cell cloning is not a new idea. Since 1944 it has been known that exist­ing hair fol­li­cles have the abil­ity to grow new hair when implanted elsewhere.

Recent research shows that bald mice can grow hair after being implanted with “blank slate” stem cells. (These are dif­fer­ent to the embry­onic stem cells that gen­er­ate so much controversy).

Stem cell cloning is not real cloning in the true sense of the word. But, it is very sim­i­lar because hun­dreds of hair fol­li­cles can be pro­duced from just one donor fol­li­cle. (Fol­lic­u­lar mul­ti­pli­ca­tion or fol­lic­u­lar cell regen­er­a­tion are more accu­rate terms).

Fol­li­cle hair trans­plant ther­apy is still in a stage of research and test­ing, and so is not yet avail­able as an alter­na­tive to con­ven­tional hair transplants.

How­ever, this treat­ment (which is also known as fol­lic­u­lar cell implan­ta­tion) will involve the fol­low­ing pro­ce­dure — A scalp biopsy is first taken to obtain a few healthy hair fol­li­cles. (This uses a local anes­thetic and takes about 30 minutes).

The extracted fol­li­cles are then dis­sected to obtain the papilla, each of which con­tains between 200 and 400 der­mal papilla cells (DPC’s).

These cells are then incu­bated in cul­tures to pro­duce hun­dreds of thou­sands of new papilla cells. This process takes about 8 weeks.

The DPC’s are then implanted (injected) into a bald area of the scalp and release cytokines (chem­i­cal sig­nals) that tell the skin to start pro­duc­ing new hair fol­li­cles.
Not as sim­ple as it sounds.  A new hair fol­li­cle is made from epithe­lial cells. But, the growth cycle of a fol­li­cle is gov­erned by DPC’s. So, both epithe­lial cells and DPC’s are needed to pro­duce a follicle.

Also, DPC’s don’t only orig­i­nate from the papilla — many migrate from the der­mal sheath into the papilla dur­ing the hair growth cycle, and then migrate back out again once the cycle is complete.

The added com­plex­ity of epithe­lial cells and der­mal sheath involve­ment in the process of cre­at­ing new fol­li­cles has pre­sented addi­tional prob­lems that must be solved if this type of ther­apy is ever to work successfully.

Prob­lems with stem cell cloning and fol­li­cle hair transplants

Even though stem cell cloning for fol­li­cle hair trans­plants has man­aged to pro­duce hair re-growth in about 70% of vol­un­teers in one very small trial, there are sev­eral areas of dif­fi­culty con­cern­ing this “ther­apy of the future.”

1.  The cul­tur­ing tech­nique must pre­serve the stem cell’s abil­ity to repro­duce hair, and ensure that a sig­nif­i­cant num­ber of DPC’s can be grown within that culture.

2.  Any hair pro­duced must be of an accept­able stan­dard to the client (i.e., thick, strong, healthy hair growth).

3.  The implan­ta­tion method must guar­an­tee that thou­sands of implan­ta­tions per client will pro­duce accept­able and stan­dard­ized hair growth for the client.

4.  An incon­sis­tent num­ber of fol­li­cles may be pro­duced — even if the same quan­tity of cells are injected into the scalp (i.e., as were injected into another area, or in another patient) hair growth can vary from one area to the next, and from one patient to another.

5.  Nor­mal hair growth has an even den­sity (dis­tri­b­u­tion) through­out the scalp. But, trans­planted cells can lump together and then cause hair growth to be patchy.

6.  Reg­u­lar hair growth is direc­tional (nor­mally it’s in a clock­wise direc­tion around the ver­tex). But the hair grown from implanted cells could be at any angle. This, of course, would give a very shabby look­ing result that’s unac­cept­able to the patient.

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